William Powell

Nick Charles

Myrna Loy

Nora Charles

Lucile Watson

Mrs. Marta Charles

Gloria DeHaven

Laura Belle Ronson

Anne Revere

Crazy Mary

Helen Vinson

Helena Draque

Harry Davenport

Dr. Bertram Charles

Leon Ames

Edgar Draque

Donald Meek

Willie Crump

Edward Brophy

Brogan

Lloyd Corrigan

Dr. Bruce Clayworth

Anita Sharp-Bolster

Hilda

Ralph Brooke

Peter Berton

Donald MacBride

Police Chief MacGregor

Morris Ankrum

Willoughby Peavy

Nora Cecil

Miss Peavy

Minor Watson

Sam Ronson

Irving Bacon

Tom

Virginia Sale

Tom's Wife

Asta Jr.

Asta

Joseph Crehan

Clancy - Policeman at Railroad Station (uncredited)

Tom Dugan

Studs Lonnegan (uncredited)

Wally Cassell

Bill Burns (uncredited)

Edward Gargan

Mickey Finnegan (uncredited)

Rex Evans

Fat Man in Train Passageway (uncredited)

Charles Halton

R.T. Tatum (uncredited)

Paul Langton

Tom Clayworth (uncredited)

Etta McDaniel

Ronson's Maid (uncredited)

Clarence Muse

Porter on Train (uncredited)

Robert Emmett O'Connor

Baggage Attendant on Train (uncredited)

Garry Owen

Pool Player (uncredited)

Jack Perry

Man in Pool Hall Brawl (uncredited)

William H. O'Brien

Train Passenger (uncredited)

Oliver Blake

Reporter (uncredited)

Tom Fadden

Train Passenger in Passageway (uncredited)

Sam Flint

Hotel Clerk (uncredited)

Harry Hayden

Train Conductor (uncredited)

Mitchell Lewis

Third Man Outside Barber Shop(uncredited)