Jack Black

Zed

Michael Cera

Oh

Oliver Platt

High Priest

David Cross

Cain

Christopher Mintz-Plasse

Isaac

Vinnie Jones

Sargon

Hank Azaria

Abraham

Juno Temple

Eema

Olivia Wilde

Princess Inanna

June Diane Raphael

Maya

Xander Berkeley

King

Gia Carides

Queen

Horatio Sanz

Enmebaragesi

David Pasquesi

Prime Minister

Matthew Willig

Marlak

Harold Ramis

Adam

Rhoda Griffis

Eve

Gabriel Sunday

Seth

Eden Riegel

Lilith

Kyle Gass

Zaftig the Eunuch

Bill Hader

Shaman

Marshall Manesh

Slave Trader

Rion Hunter

Bedouin Sheik

Gene Stupnitsky

First Guard

Lee Eisenberg

Sodom Sentry

Eric Gipson

Sodom Vendor

Lacie Manshack

Banana Girl

Matt Besser

Guy in Crowd

Drue Franklin

Squanto

Weston Hollenshead

Kid Stoner

Paul Scheer

Bricklayer

Joaquin Townsend

Slave Child

Bryan Massey

New Guard

Keet Davis

Desert Soldier

Tim Hilton

Pedestrian Villager

Ashley Nicole Caldwell

Gold Statue

Mark Cotone

Angry Baker

Jack Walker

Village Child

Jamal Sims

Dancer

Paul Benshoof

Dancer

Kelly Connolly

Dancer

Leslie Geldbach

Dancer

Katherine Miller

Dancer

Michael Morris

Dancer

Sarah Christine Smith

Dancer

Paul Rudd

Abel (uncredited)

Laura McDavid

Gatherer (uncredited)